Don't make it more complicated than it actually is, or you'll end up like Erasmus Montanus. The causality of hyper-inflation is a pretty simple principle to understand. And the effects are visible. I was there, in pre-war Yugoslavia, when my mother cashed in 1000 NOK for what to my 12 year old eyes looked like Scrooge McDuck amounts of Yugo Dinars. We had to get extra bags to carry it all. Meanwhile everywhere we turned, people were in despair because all value was evaporating. And what was left over, was heavily rationed.
It is an inhibitor of whats called the Integrated Stress Response. A “normal” cell is one that uses glucose to create energy and create additional fuel for mitochondria to make LOTS of fuel (caveat- not every cell, this varies a lot, but often enough). This fuel is used to power everything and keep it working well.
Under stress, a lot of that normal machinery is shut down, which means a neuron may not communicate anymore, as all these normal things need lots of energy.
I am not as sure on this point, but I think stress generally means a cell takes in less glucose; it shuts down mitochondria, and overall produces less energy.
Excessive blood sugar, then insulin spikes, and over time type 2 diabetes. It used to take a life time to acquire type 2 diabetes and historically it was called adult onset diabetes.
The first case of type 2 diabetes in a child was only diagnosed in the 1983...now it’s common in children. Generally about 1/3 of the US is prediabetic, this population will generally also suffer from other chronic (metabolic) conditions like inflammation and obesity.
