I would add another negative to the list from personal experience. About a year ago I built a used server dual Xeon home server with e5-2680v2s. Now the pass mark scores per chip are about 15,000 but the power draw overall can get quite high. If you’re in an area with more expensive kwh I would recommend looking into something like a threadripper or a more efficient and newer cpu.
If it's a home server doing not much most of the time, an intel skull/hade canyon can be a good choice. It can be really powerful when it needs to be, is effectively a laptop cpu the rest of the time, so not drawing much power. The only inconvenience is that it has no ipmi and it becomes really loud under heavy load.
Also you can sort of get 10gbe through a thunderbolt adapter but I ran into some compatibility issues with hyper-v.
That depends on where you put it and how much uptime the machine sees. My cold storage NAS draws 70W idle, but its up time is at most a few hours per week - and I essentially got it for free. Since the 12 disk file server case sits in the basement it doesn't bother anyone with the turbines running.
I thought about going dual Xeon for my desktop, but found that I don't often need that much power (at home) to warrant excessive power draw you mention.
