I use a FT05 case for one of my desktops; besides being excellent thermally, having the motherboard rotated 90° with the rear i/o facing upwards is nice (also no gpu sag).
I built a custom case with a rotated motherboard like this, with a huge furnace filter on the intake and 8 fans (well in excess of what's needed for cooling) to clean my room air.
I switched first to Gentle Typhoons, then the new Noctua NF-A12×25.
The cheap-o original fans were quiet at low speed but hardly moved any air, and at high speed they made tons of wind noise; I think the airfoils were stalling or something.
The Gentle Typhoons were reasonably wind-noise quiet even at high speed, but made a high-pitched hissing from the bearings at all speeds, and a groaning rumble from the motors at low speed.
The Noctuas are much quieter at 1000 rpm, almost inaudible relative to the 4 hard drives, and make fairly innocuous white noise at high speed.
Since we’re on the topic of computer hacks, I turned off the heat in my room and farmed litecoin for a winter with my PC. My room was warm and toasty, and I sold the litecoin and bought a new video card!
I also currently have my home server in a closet with the seeds I’m starting so the soil stays around 80 degrees (f).