The common theme there is constrained proximity. To give random chance more of a chance.
My favorite illustration was a video of simulated icosahedral viral capsid assembly. The triangular panels were tethered together to keep them slamming into each other. Even then, the randomness and struggle was visceral. Lots of hopeless slamming; tragic almost but failing to catch; being smashed apart again; misassembling. It was clear that without the tethers forcing proximity, there'd be no chance of successful assembly.
Nice video... it's on someone's disk somewhere, but seemingly not on the web. The usual. :/
> yeast
Nice example. For a temperature/jiggle story, I usually pair refrigerating food to slow the bacterial jiggle of life, with heating food to jiggle apart their protein origami string machines of life. With video like https://www.youtube.com/watch?v=k4qVs9cNF24 .
> Compartmentalizing
I've been told the upcoming new edition of "Physical Biology of the Cell" will have better coverage of compartmentalization. So there's at least some hope for near-term increasing emphasis in introductory content.
Coincidentally I'm previewing PBotC just now. It looks really promising. Do you know roughly when the new edition is expected? Or if you have any favorite books on how things work at that scale, I'd be grateful for the pointer. (I've read a popular book by David Goodsell and am halfway through a somewhat deeper one.)
I've found the bionumbers database[1] very helpful. Google scholar and sci-hub for primary and secondary literature. But books... I'd welcome suggestions. I'm afraid I mostly look at related books to be inspired by things taught badly.
The bionumbers folks did a "Cell Biology by the Numbers" book... the draft is online[2].
Ha, they've done a Covid-19 by the numbers flyer[3].
If you ever encounter something nice -- paper, video, text, or whatever, or even discussion of what that might look like -- I'd love to hear of it. Sorry I can't be of more help.
My favorite illustration was a video of simulated icosahedral viral capsid assembly. The triangular panels were tethered together to keep them slamming into each other. Even then, the randomness and struggle was visceral. Lots of hopeless slamming; tragic almost but failing to catch; being smashed apart again; misassembling. It was clear that without the tethers forcing proximity, there'd be no chance of successful assembly.
Nice video... it's on someone's disk somewhere, but seemingly not on the web. The usual. :/
> yeast
Nice example. For a temperature/jiggle story, I usually pair refrigerating food to slow the bacterial jiggle of life, with heating food to jiggle apart their protein origami string machines of life. With video like https://www.youtube.com/watch?v=k4qVs9cNF24 .
> Compartmentalizing
I've been told the upcoming new edition of "Physical Biology of the Cell" will have better coverage of compartmentalization. So there's at least some hope for near-term increasing emphasis in introductory content.