It also published [0] which seemed to be the ultimate source for the 'ibuprofen kills COVID-19 patients' scare, every article I found on ibuprofen+coronavirus led back there, which matter-of-factly states:
> ACE2 can also be increased by thiazolidinediones and ibuprofen.
The closest thing I could find [2] to a source for that was [1]:
> NSAIDs [Non-Steroidal Anti-inflammatory Drugs, which includes ibuprofen] might affect how Covid-19 binds to human cells, according to Dr. Yogen Kanthi, assistant professor of cardiology at the University of Michigan, who studies inflammation.
> “There is data from basic science studies that have shown that Covid-19 itself binds to a protein at the surface of cells called ACE2,” he said. “There is a hypothetical risk that giving NSAIDs like ibuprofen could increase levels of ACE2 shown in animal models, but not in patients.”
> ACE2 can also be increased by thiazolidinediones and ibuprofen.
The closest thing I could find [2] to a source for that was [1]:
> NSAIDs [Non-Steroidal Anti-inflammatory Drugs, which includes ibuprofen] might affect how Covid-19 binds to human cells, according to Dr. Yogen Kanthi, assistant professor of cardiology at the University of Michigan, who studies inflammation.
> “There is data from basic science studies that have shown that Covid-19 itself binds to a protein at the surface of cells called ACE2,” he said. “There is a hypothetical risk that giving NSAIDs like ibuprofen could increase levels of ACE2 shown in animal models, but not in patients.”
[0] - https://www.thelancet.com/pdfs/journals/lanres/PIIS2213-2600...
[1] - https://kvia.com/health/2020/03/17/france-says-ibuprofen-may...
[2] - https://news.ycombinator.com/item?id=22611363