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DOI 10.3389/fpsyg.2016.01053 (“the findings suggest that GnRH treated CPP girls do not differ in their cognitive functioning, behavioural, and social problems from the same age peers”, albeit findings on emotional regulation and reactivity are inconclusive - which is not the same thing as bad, just their experiment design didn’t give them a clear answer).

DOI 10.10.1016/j.psyneuen.2015.03.007

We have no strong evidence that it is unsafe in humans, and a bunch of evidence that it is safe.

The Economist is a weird source for a medical research discussion.



Hey, thanks for the link! I'm not sure that the article is too relevant though, since it is about the effects of puberty blocker in treatment of precocious puberty.

Which brings us to the reason why I linked to the Economist article; it gives a pretty good overview about the various concerns of various groups and gives some rudimentary overview about the current understanding. It's pretty hard for laypersons to really understand the jargon in all these papers and it's easy to overlook subtle but important details.

I think my point still stands; we don't know enough yet. We need more research.


The second article was about trans kids.

Aside from that, sure. I’m up for more research (that doesn’t harm trans kids - smarter people than I know experiment designs which don’t result in people receiving subpar treatment for years on end). More research on trans people is welcome, there’s fuck-all of it out there, and now the meantime, we must do our best to use what we do know to help people.


> More research on trans people is welcome, there’s fuck-all of it out there, and now the meantime, we must do our best to use what we do know to help people.

I think we can agree on that.


From the wikipedia:

“Research on the long term effects on brain development is limited.”

https://en.wikipedia.org/wiki/Puberty_blocker




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