Why do you want a 454? I mean, as awesome as it would be to know your own genetic code, it would be of no practical use to you, even if you had a full featured tool to explore it.
And don't even get me started on personal epigenome or miRNA-omes.
Well, mostly I was just trying to see if they were headed in that direction... but there might be some logic in that SNPs do not always represent the functional differences in genes - they generally have their power because they are correlated with the nearby functional difference. The full set of DNA changes might be more precise in terms of really really pinpointing the right genes. But, I guess the true power comes with correlating everybody and their phenotypes together, in which case it doesn't matter if you're looking at unexplainable SNPs or not.
