Broad topic, I was thinking just about this while I was in the gym.
What's a problem you've seen that you just want to get solved? Any problem, big or small, just spit it out, as big as world hunger, as theoretical as string theory, or as specific as twitter API architecture.
Perhaps something good will come of this? I'm sure this has been done before, but you learn something new every time.
Bonus points if you can take out IE7 as well.