ALT+S is also save in XCode with default key mappings for a standard keyboard. I hit save habitually while coding. I've sent several incomplete emails hitting that. I've started typing up my emails in Vim and pasting into Outlook when I'm done.
I was going to ask why the downvotes but today I switched to a newer Dell keyboard, the kind that looks like an Apple ripoff. I had the Dell KB212-B before. My 'Modifier Key' settings have always been the default. Alt mapped to Command on my old keyboard, "Windows" maps to Command on this one. Searching seems to suggest Windows to Command is the norm. I sort of liked Alt to Command since it mimicked the Apple layout more closely. Hmmm, which to choose?