Gwern's writings on nootropics are particularly fascinating. They read like the works of a mad scientist (in a good way). Erudite, meticulous, and also a tiny bit reckless. Gwern treats himself like a human guinea pig, then documents and analyzes the results more carefully than I've seen in some research papers. The whole process, furthermore, reads like a dialogue between Gwern and the reader. To be more precise, it reads like a dialogue between Gwern and Gwern's imagined idea of a highly intelligent reader -- a reader whose place you find yourself wanting to fill.
Gwern's archive is eccentric, to say the least. But it's one of the best places on the web to lose oneself for an afternoon.
Honestly, his writeups on most things are pretty spot on.